Protein structure prediction: Concepts and applications
نویسندگان
چکیده
منابع مشابه
Medical Informatics: Concepts and Applications
Medical Informatics is a developing body of knowledge concerned with the use of information and communication technology in support of medical research, education and also for promoting health care delivery. The field focuses on the biomedical information, patient data, and also acquisition, storage, retrieval and optimal use of information for problem solving and decision making. The goal of m...
متن کاملAdvances in Protein Structure Prediction: Algorithms and Applications
The design of scoring functions (or potentials) for threading, differentiating native-like from non-native structures with a limited computational cost, is an active field of research. We revisit two widely used families of threading potentials: the pairwise and profile models. To design optimal scoring functions we use linear programming (LP). The LP protocol makes it possible to measure the d...
متن کاملApproaches to Protein Structure Prediction and Their Applications
Introduction Proteins are one of the major biological macromolecules performing a variety functions such as enzymatic catalysis, transport, regulation of metabolism, nerve conduction, immune response etc. The three-dimensional structure of a protein is responsible for its function. In this paper I wish to give an overview of the need for protein structure prediction, the different approaches av...
متن کاملIdentification and application of the concepts important for accurate and reliable protein secondary structure prediction.
A protein secondary structure prediction method from multiply aligned homologous sequences is presented with an overall per residue three-state accuracy of 70.1%. There are two aims: to obtain high accuracy by identification of a set of concepts important for prediction followed by use of linear statistics; and to provide insight into the folding process. The important concepts in secondary str...
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ژورنال
عنوان ژورنال: Biochemistry and Molecular Biology Education
سال: 2007
ISSN: 1470-8175,1539-3429
DOI: 10.1002/bmb.8